Director - Oncology Safety Science & Discovery, Tumor Targeted Delivery
Company: National Black MBA Association
Location: Gaithersburg
Posted on: October 6, 2024
Job Description:
Associate Director/Director - Oncology Safety Science &
Discovery, Tumor Targeted DeliveryAt AstraZeneca, it is our bold
ambition to eliminate cancer as a cause of death. This is
underpinned by our rich pipeline striving to deliver innovative
treatment options for patients. Oncology Safety colleagues
contribute to this ambition by accelerating innovative and expert
non-clinical safety science.We are looking to recruit an Associate
Director/ Director, Safety Science & Discovery to contribute to the
discovery of novel targeted oncology medicines, including Antibody
Drug Conjugates and Radioconjugates. In collaboration with
scientists across our Oncology R&D organization, this role will
develop investigative toxicology strategies to address drug target-
and modality-related safety risks, drive progression of drug
discovery programs, and develop our safety science to inform the
design and selection of novel drug candidates. This role will be
based at our vibrant R&D site in Gaithersburg, MD (Washington
DC area).Within AstraZeneca, we place a strong emphasis on talent
development. You will be able to develop your knowledge and skills
by working together with experts and leaders in Oncology R&D,
safety science, pharmacology, toxicology, drug discovery and
development, imaging, pathology, and translational science.Job
responsibilities include:
- As core member of multi-disciplinary drug discovery teams, you
will direct investigative/discovery toxicology strategies to
predict, assess and mitigate target- and modality-related safety
risks in discovery programs, with a focus on Antibody-Drug
Conjugates and Radioconjugates.
- Apply investigational and mechanistic safety studies through in
vitro experimental capabilities to predict clinical safety and
advise decision-making in drug discovery and development
programs.
- Develop and implement innovative solutions and research
proposals to pursue groundbreaking science and technologies in line
with business needs versus safety aspects.
- Maintain expertise in regulatory requirements and preclinical
safety approaches applied to Antibody Drug Candidates and
Radioconjugates and awareness of industry trends.
- Publish in high quality, peer-reviewed journals, present at
internal scientific meetings and external conferences.Skills and
Requirements:
- Excellent scientist with a PhD (or equivalent) in Biology,
Toxicology, Pharmacology, Oncology, Immunology or related field, a
strong scientific track record, and a willingness to challenge
conventional thinking.
- A proven understanding of drug discovery and development (5+
years of experience), with a strong track record of independent
research in industry, biotech, or academic setting.
- Expertise in Oncology and targeted therapeutics, including
understanding of drug safety aspects of ADCs and/or
Radioconjugates.
- Experience with design and execution of in vitro and/or in vivo
experiments to determine the effects of therapeutics on biological
systems.
- The ability to build an understanding of biology around novel
drug targets and pathways, develop testable hypotheses, and drive
scientific learning.
- A collaborative, team-oriented approach, able to solve problems
in a goal-focused fashion with capacity to coordinate tasks across
multiple projects.
- Excellent communication, presentation, interpersonal and
influencing skills across levels/subject areas with a strong desire
to drive personal development.
- Level of the role (Associate Director/Director) will be based
on experience, understanding of drug discovery and development, and
track record of successful contributions to progression of drug
projects and scientific accomplishment.Why AstraZeneca?At
AstraZeneca, we follow the science to explore and innovate. We are
working towards treating, preventing, modifying and even curing
some of the world's most complex diseases. Here we have the
potential to grow our pipeline and positively impact the lives of
billions of patients around the world. We are committed to making a
difference by fusing data and technology with the latest scientific
innovations to achieve the next wave of breakthroughs. If your
passion is science and you want to be part of a team that makes a
bigger impact on patients' lives, then there's no better place to
be!Ready to make a difference? Apply now!
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Keywords: National Black MBA Association, Rockville , Director - Oncology Safety Science & Discovery, Tumor Targeted Delivery, Executive , Gaithersburg, Maryland
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